"In fact, Parkinson''s disease is not a simple degenerative disease, but an autoimmune disease based on progressive disease!"
After saying this, Yang Lan and Qi KaiDun changed their faces!
Because the meaning behind this sentence may overturn the previous cognition of Parkinson''s disease!
So many years of research on Parkinson''s disease, no one has ever thought of him together with autoimmune diseases!
What is autoimmune response?
Under normal circumstances, the human immune system will not respond to its own components, which is called autoimmune tolerance.
However, when our body''s autoimmune tolerance mechanism is maladjusted or destroyed, it leads to the injury of our own tissues and organs or the immunopathological state of abnormal function.
To put it simply, generally speaking, the defense system does not hit its own people, but when some special reactions occur, its own soldiers do not know their own people and begin to hit their own people.
This is the autoimmune disease of the human body.
If you say so... In fact, all the civil war is autoimmune reaction, right?
Up to now, to tell the truth, even Chen Cang didn''t react!
He never thought that Parkinson''s disease was an autoimmune disease to some extent!
This result is fundamentally inconsistent with almost all existing Parkinson''s ideas!
Even Chen Cang began to doubt!
"Could it be wrong?"
Yang Lan and Qi Kai were breathless and looked at each other solemnly.
Three people just stayed in the laboratory without saying a word.
Chen Cang looked at the status of scientific research assistance and guidance. At this time, the remaining time is less than one day.
Time must not be wasted.
At this time, just like Copernicus who discovered the heliocentric theory, they overturned the long-standing geocentric theory.
However, once this concept comes out, the received will become a huge flood of ideas.
The room is very quiet!
Even the air seemed stagnant.
None of them expected such a terrible discovery.
long time!
A word sounded in the room:
"Professor Chen, this time... You''re going to stand opposite all Parkinson''s researchers!" Yang Lan''s voice was a little excited.
In the future, Qi Kai''s firm voice sounded:
"No! It''s us!"
"What are you afraid of? Who says the idea of a few people is wrong?"
"Truth is often in the hands of a few!"
Chen Cang smiled. He felt that he was right.
After several days of sleepless and restless sleep and food, Chen Cang has definitely improved and improved his scientific research concept.
Chen Cang said for a long time: "three people, a lot!"
In a word, let Qi Kai and Yang Lan warm their hearts.
To tell the truth, they have always been in an auxiliary position and have been able to help Chen Cang.
But Chen Cang''s recognition warmed their hearts.
Qi Kai said directly, "Professor Chen, next... What should we do?"
Now!
Chen Cang has become the core of this humble scientific research team.
After a few days of research and development, they seem to realize that this young man seems to have unlimited potential waiting to be tapped.
Yang Lan also nodded firmly: "yes, Professor Chen, what should you do next?"
"We listen to you!"
Chen Cang smiled gratefully, "OK!"
With that, Chen Cang directly picked up his pen and wrote on the big screen: "the current progress is here. We just found that these patients have autoimmune reaction in human blood. It is speculated that it comes from broken folding α- Synuclein! "
"So, the next work is two! First, the first is to seek the theoretical basis! The second is the simulation test!"
"Director Yang, you are an expert in the field of scientific research. You are more professional in nervous system research. I hope you can find papers, literature and theoretical basis conducive to our results in the shortest time!"
"Director Qi, your next job is to simulate animal experiments to prove the existence of autoimmune response!"
"I''m responsible for finding the key elements!"
Chen Cang''s voice fell!
The three gently touched their fists: "come on!"
A nearly 60 year old president Qi.
A director Yang just after menopause.
A Chen Cang less than 30.
Continue to start the road of seeking truth!
Time for Chen Cang, every minute and second seems a little extravagant!
the second day!
Yang Lan exclaimed in surprise, "Professor Chen, great discovery!"
"The idea that a malfunctioning immune system caused Parkinson''s disease dates back nearly 100 years. But so far, no one has been able to connect the two."
"However, in a study in 2014, Dr. Sulzer''s laboratory has confirmed that dopaminergic neurons affected by Parkinson''s disease are relatively fragile because they contain proteins recognized as exogenous substances by the immune system on their cell surface!"
The two messages immediately inspired Chen Cang and Qi Kai!
Qi Kai''s eyes brightened: "that is to say... Our theory may be right!"
Chen Cang smiled!
What is the most important thing about scientific research?
Scientific research confidence!
What is scientific confidence?
That is, no matter what others say, you must believe that your research route is right.
This is the only driving force for you to keep going down and forward!
Good news keeps coming!
Early the next morning.
A strange cry broke the silence of the laboratory.
Qi Kai''s red eyes burst at this time!
He shouted excitedly outside the window.
This voice woke up the rooster, scolded angrily and continued to sleep!
Qi Kai is really suffocating. The accumulated depression in these days has finally been vented!
Chen Cang slept on the ground and just lay on the experimental platform. Yang Lan used the only bench.
They were awakened by this voice!
Qi Kai didn''t care to apologize. He hurriedly said, "don''t sleep, get up, you''ve found something!"
Chen Cang and Yang Lan were originally bleary eyed. Hearing these words, they instinctively stood up quickly.
"What''s the matter?"
"What''s the matter!"
Qi Kai excitedly handed the experimental results to the two people and said excitedly, "we''re right! Absolutely right!"
"This is definitely an autoimmune response!"
"You see, we exposed blood samples from 67 Parkinson''s disease rats and 36 healthy rats with matching shape and size, and found them in neurons!"
"This is α- Synuclein fragments and other protein fragments! "
"We analyzed these samples to find out which protein fragments trigger the immune response!
Surprisingly, few immune cell activities were observed in blood samples from healthy rats.
In contrast, blood samples from rats with Parkinson''s disease had been exposed before α- Synuclein, obviously able to recognize this protein!
What does that mean?
Explain these α- Synuclein fragments showed a strong immune response. "