This discovery made the whole institute boiling!


    The discovery of this polymerase seems to directly verify the common ground between Parkinson''s and Alzheimer''s in neurodegenerative diseases!


    However, this is not the key.


    The most important thing is that Parkinson''s attack finally has a breakthrough!


    Chen Cang himself did not expect that enzyme temptation so awesome!


    Directly found the culprit''s polymerase.


    After the discovery of polymerase, all departments began clinical research and various experimental work!


    The progress of the experiment is almost by leaps and bounds!


    Everyone is immersed in this breakthrough like progress!


    Tedanis now has no regrets about joining Chen Cang''s camp.


    He believes that even kangxidin can''t do this, and poly adenosine diphosphate ribose polymerase-1 can be isolated!


    This polymerase belongs to ribose polymerase, which exists in mitochondria and ribose of cells. It is extremely difficult to separate!


    For a time, the news that Professor Chen isolated this polymerase spread throughout the Institute!


    Everyone was shocked!


    Professor Chen has such talent in the field of scientific research?


    Creatively invented a technique called foam separation.


    For a time, Chen Cang''s reputation was boiling again.


    However, the most important thing is not Chen Cang''s reputation.


    But boss Chen''s innovative discovery, which directly extracted polyadenyldiphosphate ribose polymerase-1!


    The research of this enzyme on Parkinson''s disease is also increasing day by day!


    Soon, tedanis led the team to say that the main function of this polymerase is to repair DNA widely in the nucleus!


    Under normal conditions, after the polymerase detects DNA damage, it will be activated and repaired!


    However, when the DNA cannot be repaired due to the case environment, this polymerase will be over activated!


    Thus, it leads to degenerative lesions of the nervous system, which aggravates folding α- The growth of synuclein induces Lewy body again... Thus a series of complex processes lead to the aggravation of Parkinson''s disease!


    Tedanis''s discovery brightened Yang Lan''s eyes.


    Qi Kai and Yang Lan quickly started the animal experiment!


    Animal experiment is a link close to the correct answer!


    The emergence of theoretical basis makes this experiment more and more expected.


    Obviously, once the conclusion is reached, it will shock the world.


    During the study!


    When Yang Lan and Qi Kai conducted animal experiments on Parkinson''s rats.


    Found more and more terrible and even shocking problems!


    The human body has a rich and perfect feedback system.


    The special state of Parkinson''s disease will make the regulation of this polymerase lose the opportunity of front and back feedback!


    Similarly, the presence of this polymerase also aggravates the folding of Parkinson''s patients α- The increase of synuclein further aggravates the condition of Parkinson''s disease.


    This forms a process!


    vicious spiral!


    you ''re right!


    Parkinson''s made polymerase out of limit.


    Polymerase accentuates folding α- Synuclein, aggravated Parkinson''s disease!


    In this way, it seems to form a closed loop.


    If one link is not broken, the cycle will become more serious.


    A week later!


    When Chen Cang was in the hospital, Qi Kai called Chen Cang directly to the research institute!


    Pass a copy of the information to Chen Cang!


    "Professor Chen, look at this!"


    Chen Cang was stunned. After he opened it and saw the topic, he was stunned in situ!


    “ α- Neurotoxicity of synuclein! "


    Chen Cang quickly began to look up.


    At this look, Chen Cang couldn''t stop it!


    Because tedanis, their study found that folding is pathological α- Synuclein aggregates can spread between brain neurons!


    Moreover, this pathological α- Synuclein will also become a seed, inducing normal growth α- Synuclein, leading to degeneration of the nervous system!


    After seeing this scene, Chen Cang was stunned!


    Qi Kai couldn''t help but say, "now it''s finally explained why the mortality of Parkinson''s mice has increased!"


    "Because of folding α- Synuclein is contagious! "


    "And this polymerase is the most critical intermediate!"


    Tedanis said excitedly, "as long as we solve this polymerase and reasonably inhibit it, we can directly delay the onset of Parkinson''s disease!"


    Zhang Mu shook his head: "not only that!"


    "The most important thing for Parkinson''s is not late treatment, but early prevention!"


    When they heard the sound, they immediately remembered it carefully!


    Zhang Mu continued, "this is a vicious cycle!"


    "As long as there is folding pathology α- Synuclein will certainly breed a variety of polymerases, and similarly, polymerases aggravate the folding process α- Synuclein! "


    "In this way, the key is how to find the folding as soon as possible α- Synuclein, timely intervention through surgery and drugs! "


    Zhang Mu''s words made everyone excited.


    Yes!


    In this way, it seems that they have found a good way to overcome Parkinson''s disease as soon as possible.


    Treatment is no longer the purpose!


    But early discovery and early intervention!


    "How to check the folding of the human body α- Synuclein? "


    "Yes, how can we find that people have Parkinson''s disease as soon as possible?"


    you bet!


    Parkinson''s disease itself is a symptomatic disease.


    Only with performance can it be found.


    It''s impossible for everyone to take a census α- Synuclein?


    This must be unrealistic!


    Can''t Parkinson''s be prevented?


    Thinking of this, everyone couldn''t help sighing.


    What a pity.


    It was not easy to make such a breakthrough.


    If it can be detected in advance, the patient will save a lot of trouble.


    How can we find out in advance?


    At this time, Chen Cang''s eyes suddenly brightened.


    He thought of a big baby!


    The new technology he once sold to Google, that is, the new technology that made a profit of $1 billion for Chen Cang: "brain stereotactic technology!"


    This new brain stereotactic technology has a special ability: DTI technology!


    That is, MR diffusion tensor imaging!


    It can observe the integrity and connectivity of tissue structure in vivo, and is conducive to judge the damage degree and scope of white matter fiber bundles of various diseases.


    At the same time, it can also respond to subtle changes in the brain of patients with mental diseases. In addition, DTI technology can also display the direction of nerve conduction bundle in brain white matter and realize fine imaging of human central nerve fibers.


    Under the guidance of DTI technology, the individual differentiation of patients with Parkinson''s disease can be accurately displayed and located. At the same time, it can be fused for three-dimensional image reconstruction surgery to guide doctors to perform accurate and efficient surgery.


    Chen Cangshi didn''t expect it!


    After such a big circle.


    The core technology is still in their own hands!


    ……


    PS: there are too many materials to check, but we can''t write blindly, which means we need to take every knowledge point seriously.


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